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contempt, it can be particularly poisonous for relationships," he said. But, he added, "everybody also knows married couples who bicker all the time, but their marriages seem to work just fine. Other couples have one argument and they're in divorce court."So why can some couples tolerate swings in emotion better than others? The researchers targeted a gene that affects serotonin, a brain chemical that's considered crucial to mood and well being. Their goal: to figure out if it's connected to the inner workings of a marriage.For the study, published online Oct. 7 in the journal Emotion, the researchers examined DNA samples from 125 long term spouses in the San Francisco area who were tracked over 20 years for research into marital satisfaction. The participants, mostly white, were all middle aged or older at that time.At issue is a genetic variant called 5 HTTLPR. Everyone receives a copy of this variant from each parent. About 20 percent of those in the study had two short 5 HTTLPR "alleles" (types), one of three possible configurations. Those people were more likely than those with one or two long alleles to be affected by the emotional level of a marriage unhappier when there was a lot of negative emotion, such as fighting, and happier when there was a lot of positive emotion, Levenson said.The effects of this genetic trait are "like amplifiers, like the knob on your hi fi where you turn up the music," Levenson said. "If the music is really bad, it will be more unpleasant. And if it's really good, it'll be more pleasant. They turn up your sensitivity to the emotional quality of the music