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infection and that over the counter cold medications won work any better against it than they will against other respiratory illnesses. However, there are prescription antiviral agents (Tamiflu) that can shorten the course and severity of illness if started promptly.Even though cold medicines for children don work, most come with labels describing promising relief for many of the symptoms that accompany the illness: congestion, runny nose, cough, thick mucus, aches and fever. Let look at the evidence.One of the prime ingredients in many cold medicines are antihistamines. Histamine is a chemical released by the body if a person is allergic to things such as pollen, dust or animals. Histamine causes blood vessels to swell, which in turn causes congestion, runny nose, itchy eyes and cough from postnasal drip. Antihistamines work by blocking the effects of histamine.It been shown in adults that histamine is released by some of the viruses that cause colds. As a result, antihistamines help to dry nasal secretions with certain colds.One of the side effects of the antihistamines used in cold medicine is sedation. Doctors sometimes recommend these drugs for their sedating properties that is, to help sick children sleep. There are limited data to show this works. But in fact some children become agitated or develop other side effects on antihistamines, and that one of the reasons the American Academy of Pediatrics does not recommend using cold medication for its sedating properties.The newer antihistamines found in many allergy medicines have no effect on the symptoms of a cold.Nasal passages are lined